DNA Testing Companies Overview

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DNA Test Companies with focus on genalogy (ancestry, genetic relatives).

FTDNA (US), iGENEA (EU)

Cooperation of

338.186 tests from 2001 to 2011 (with Geneographic Project?). Tested 600,000 people (Nov. 2011). € Price is for iGENEA offers, $ for FTDNA offers. Promotion Sales in December. Shipping costs included, Credit Card (Mastercard, Visa) or Paypal.

mtDNA

  • mtDNA basic: HVR1 + Haplogroup: €79;
  • mtDNA basic plus: HVR1 + HVR2 + Haplogroup: €119;
  • mtDNAPlus: HVR1 and HVR2 + haplogroup, origins, online-updates: $159;
  • mtDNA premium: HVR1 + HVR2 + Haplogroup + Orig./Rel.: €179;
  • FMS (mtFullSequence): HVR1 / HVR2 / Coding Region + haplogroup, origins, online-updates: $299
  • mtDNA expert: full mtDNA-Sequence (FGS) + Haplogroup + Subgroup + Orig./Rel. + FamilyFinder: €699

Y-DNA

mt/Y-DNA Packages

Autosomal DNA + X-DNA

Chromosome 1 to 22 and X (no Y and mt is included!) with standard Illumina OmniExpress. Family Finder: to get in contact with relatives (people that share DNA parts) + Population Finder: $289 - €249 (was €239 in August 2011).

  • raw data download: v2 raw data has ~725,000 SNPs
  • Autosomal DNA: ~707,000 SNPs
  • X-DNA: ~18,000 SNPs

23andMe (US)

23andMe (Wikipedia - Google et.al.) Personal Genome Service from California/USA - over 75.000 Tests (4/2011)

Autosomal DNA + X-DNA + Y-DNA + mtDNA)

Illumina OmniExpress Plus customized. Ancestry services: Relative Finder (1 million loc. autosomal DNA - similarities), Global Origins, Ancestral Lineages. Subscription $207 ($99 + $9/month for 1 year) / one time $399 + ca. $64 international shipping (incl. return) = $271 or $463 (ca. €208 or €355)
Credit Card (Mastercard, Visa, etc.) - discount codes available.

  • raw data download: v3-only-data has ~960,000 SNPs
  • Autosomal DNA: ~930,000 SNPs
  • X-DNA: ~26,000 SNPs
  • Y-DNA: 1800-3000 SNPs, medium Haplogroup deepness (Tree of 2008, some main subgroup is missing)
  • mtDNA: ~2500 SNPs, deep Haplogroup clades


Other Companies

  • DNA Testing by Ancestry.com; Utah/USA, LU, London/UK, CA, AU, NZ (SorensonGenomics?)
    Y-DNA 33 or Y-DNA 46, haplogroup: $149-$179
    mtDNA: HVR 1 & 2, rCRS, Haplogroup: $179
    AncestryDNA: Autosomal test in final dev (spring 2012): 700,000 SNPs, no raw data download?
  • Lumigenix (newcomer: founded 2010): Australian-based, offering Illumina chip-based genotyping service:
    Autosomal DNA + Y-DNA + mtDNA ~ 732,000 SNPs (HumanOmniExpress+) + 2,700 Y/mt, download of raw data, ancestry analysis and information on 2000 maternal and paternal haplogroups, global similarity and global ancestry. $479 USD. Full Genome per request.
  • GeneTree - Wikipedia by Sorenson Molecular Genealogy Foundation - SMGF from Utah/USA (Wikipedia): mtDNA HVR-1,2,3; Y-DNA 46 marker
  • The DNA Ancestry Project by Genebase in USA/CA by Genetrack Biolabs in CA/USA - 100.000 samples per year: Y-DNA STR Test (44,67,91 Marker), Y-DNA SNP Haplogroup/Subclade, mtDNA HVR-1 + HVR-2, mtDNA SNP, Full mtDNA Sequencing, Autosomal DNA (15-19 STR Markers)
  • Britains DNA is active under the brand Scotlands DNA (specialises in Scottish ancestry). The company worked under the name EthnoAncestry in London & Scotland (Wilson, Cavalleri) and was active from 2004 to 2011 and offered mtDNA, Y-STR, Y-SNP and TGAC interpretation (for 23andMe or DeCodeMe Tests).
  • Oxford Ancestors - Oxford/UK - Bryan Sykes: ancestral clan mother, Y-Clan signature (paternal clan, 15 Markers)
  • GEN by GEN in Göttingen/DE: Y-Genotyping / "ancient mother" 9 Alleles
  • AncestrybyDNA, former brand of DNAPrint Genomics (Wikipedia) inactive since Feb. 2009; AncestrybyDNA-Website actualized 2011? (probably acquired by DDC / DNA Diagnostics Center in Ohio/USA): simple mtDNA, Y-DNA and Autosomal Tests (some Markers)
  • DNA Consultants from Phoenix/USA. Autosomal: test (18 Markers), ancestry, matches to populations
  • DNA Tribes Genetic Ancestry Analysis in Virginia/USA - Wikpedia: Autosomal Test (15-27 STR Markers)

No Ancestry / Genealogical focus

  • deCODE genetics in Reykjavík, Iceland offers complete genetic scan (deCODEme) with 1.2 million SNPs (Illumina Infinium HumanIM chip) for $1,100 USD. Demo. data download should be possible.


Comparisons & Future

23andMe v3 - Family Finder v2

23andMe v3 (960,545 SNPs) to Family Finder v2 (726,183 SNPs) in Dec. 2011.[2]:

  • 699,674 in common
  • 260,871 on 23andMe v3 but not Family Finder v2
  • 26,509 on Family Finder v2 but not 23andMe v3

Possible new offers

  • Illumina HumanOmni5-Quad BeadChip Kit: 4.3 million SNPs + 0.5 million custom SNPs (6x Illumina OmniExpress, SNPs selected from the International HapMap and 1000 Genomes Projects!), the kit should be available for companies in 2012.
  • FTDNA WTY v2: FTDNA 454 testing data (since Nov. 2011), 8 million bp (30x WTY v1), prices goal under $1000, not available (spring 2012)

References

  1. Thomas Krahn, Nov. 2011, http://www.dna-fingerprint.com/static/FTDNA-Conference-2011-WalkThroughY.pdf
  2. James Lick, Comparing v3 SNP List to v2, deCODE, Family Finder, DNA-Forums.org, 06 December 2011 (Offline)