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== 23andMe (US) ==
== 23andMe (US) ==


[https://www.23andme.com/ '''23andMe'''] ([http://de.wikipedia.org/wiki/23andMe Wikipedia] - Google et.al.) Personal Genome Service from California/USA - over 75.000 Tests (4/2011)
[[23andMe]] (local), [https://www.23andme.com/ '''23andMe'''] ([http://de.wikipedia.org/wiki/23andMe Wikipedia] - Google et.al.) Personal Genome Service from California/USA - over 75.000 Tests (4/2011)
=== Autosomal DNA + X-DNA + Y-DNA + mtDNA) ===
=== Autosomal DNA + X-DNA + Y-DNA + mtDNA) ===
[https://www.23andme.com/ancestry/techniques/ Illumina OmniExpress Plus customized]. [https://www.23andme.com/ancestry/ Ancestry services]: [https://www.23andme.com/ancestry/relfinder/ Relative Finder (1 million loc. autosomal DNA - similarities)], [https://www.23andme.com/ancestry/origins/ Global Origins], [https://www.23andme.com/ancestry/lineage/ Ancestral Lineages]. Subscription $207 ($99 + $9/month for 1 year) / one time $399 + ca. $64 international shipping (incl. return) = $271 or $463 (ca. €208 or €355)<br /> Credit Card (Mastercard, Visa, etc.) - discount codes available.  
[https://www.23andme.com/ancestry/techniques/ Illumina OmniExpress Plus customized]. [https://www.23andme.com/ancestry/ Ancestry services]: [https://www.23andme.com/ancestry/relfinder/ Relative Finder (1 million loc. autosomal DNA - similarities)], [https://www.23andme.com/ancestry/origins/ Global Origins], [https://www.23andme.com/ancestry/lineage/ Ancestral Lineages]. Subscription $207 ($99 + $9/month for 1 year) / one time $399 + ca. $64 international shipping (incl. return) = $271 or $463 (ca. €208 or €355)<br /> Credit Card (Mastercard, Visa, etc.) - discount codes available.  
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* '''Y-DNA''': 1800-3000 SNPs, medium Haplogroup deepness (Tree of 2008, some main subgroup is missing)
* '''Y-DNA''': 1800-3000 SNPs, medium Haplogroup deepness (Tree of 2008, some main subgroup is missing)
* '''mtDNA''': ~2500 SNPs, deep Haplogroup clades
* '''mtDNA''': ~2500 SNPs, deep Haplogroup clades


== Other Companies ==
== Other Companies ==

Version vom 13. April 2012, 21:00 Uhr

DNA Test Companies with focus on genalogy (ancestry, genetic relatives).

FTDNA (US), iGENEA (EU)

Cooperation of

338.186 tests from 2001 to 2011 (with Geneographic Project?). Tested 600,000 people (Nov. 2011)[1]. € Price is for iGENEA offers, $ for FTDNA offers. Promotion Sales in December. Shipping costs included, Credit Card (Mastercard, Visa) or Paypal.

mtDNA

  • mtDNA basic: HVR1 + Haplogroup: €79;
  • mtDNA basic plus: HVR1 + HVR2 + Haplogroup: €119;
  • mtDNAPlus: HVR1 and HVR2 + haplogroup, origins, online-updates: $159;
  • mtDNA premium: HVR1 + HVR2 + Haplogroup + Orig./Rel.: €179;
  • FMS (mtFullSequence): HVR1 / HVR2 / Coding Region + haplogroup, origins, online-updates: $299
  • mtDNA expert: full mtDNA-Sequence (FGS) + Haplogroup + Subgroup + Orig./Rel. + FamilyFinder: €699

Y-DNA

mt/Y-DNA Packages

Autosomal DNA + X-DNA

Chromosome 1 to 22 and X (no Y and mt is included!) with standard Illumina OmniExpress. Family Finder: to get in contact with relatives (people that share DNA parts) + Population Finder: $289 - €249 (was €239 in August 2011).

  • raw data download: v2 raw data has ~725,000 SNPs
  • Autosomal DNA: ~707,000 SNPs
  • X-DNA: ~18,000 SNPs

23andMe (US)

23andMe (local), 23andMe (Wikipedia - Google et.al.) Personal Genome Service from California/USA - over 75.000 Tests (4/2011)

Autosomal DNA + X-DNA + Y-DNA + mtDNA)

Illumina OmniExpress Plus customized. Ancestry services: Relative Finder (1 million loc. autosomal DNA - similarities), Global Origins, Ancestral Lineages. Subscription $207 ($99 + $9/month for 1 year) / one time $399 + ca. $64 international shipping (incl. return) = $271 or $463 (ca. €208 or €355)
Credit Card (Mastercard, Visa, etc.) - discount codes available.

  • raw data download: v3-only-data has ~960,000 SNPs
  • Autosomal DNA: ~930,000 SNPs
  • X-DNA: ~26,000 SNPs
  • Y-DNA: 1800-3000 SNPs, medium Haplogroup deepness (Tree of 2008, some main subgroup is missing)
  • mtDNA: ~2500 SNPs, deep Haplogroup clades

Other Companies

  • DNA Testing by Ancestry.com; Utah/USA, LU, London/UK, CA, AU, NZ (SorensonGenomics?)
    Y-DNA 33 or Y-DNA 46, haplogroup: $149-$179
    mtDNA: HVR 1 & 2, rCRS, Haplogroup: $179
    AncestryDNA: Autosomal test in final dev (spring 2012): 700,000 SNPs, no raw data download?
  • Lumigenix (newcomer: founded 2010): Australian-based, offering Illumina chip-based genotyping service:
    Autosomal DNA + Y-DNA + mtDNA ~ 732,000 SNPs (HumanOmniExpress+) + 2,700 Y/mt, download of raw data, ancestry analysis and information on 2000 maternal and paternal haplogroups, global similarity and global ancestry. $479 USD. Full Genome per request.
  • GeneTree - Wikipedia by Sorenson Molecular Genealogy Foundation - SMGF from Utah/USA (Wikipedia): mtDNA HVR-1,2,3; Y-DNA 46 marker
  • The DNA Ancestry Project by Genebase in USA/CA by Genetrack Biolabs in CA/USA - 100.000 samples per year: Y-DNA STR Test (44,67,91 Marker), Y-DNA SNP Haplogroup/Subclade, mtDNA HVR-1 + HVR-2, mtDNA SNP, Full mtDNA Sequencing, Autosomal DNA (15-19 STR Markers)
  • Britains DNA is active under the brand Scotlands DNA (specialises in Scottish ancestry). The company worked under the name EthnoAncestry in London & Scotland (Wilson, Cavalleri) and was active from 2004 to 2011 and offered mtDNA, Y-STR, Y-SNP and TGAC interpretation (for 23andMe or DeCodeMe Tests).
  • Oxford Ancestors - Oxford/UK - Bryan Sykes: ancestral clan mother, Y-Clan signature (paternal clan, 15 Markers)
  • GEN by GEN in Göttingen/DE: Y-Genotyping / "ancient mother" 9 Alleles
  • AncestrybyDNA, former brand of DNAPrint Genomics (Wikipedia) inactive since Feb. 2009; AncestrybyDNA-Website actualized 2011? (probably acquired by DDC / DNA Diagnostics Center in Ohio/USA): simple mtDNA, Y-DNA and Autosomal Tests (some Markers)
  • DNA Consultants from Phoenix/USA. Autosomal: test (18 Markers), ancestry, matches to populations
  • DNA Tribes Genetic Ancestry Analysis in Virginia/USA - Wikpedia: Autosomal Test (15-27 STR Markers)

No Ancestry / Genealogical focus

  • deCODE genetics in Reykjavík, Iceland offers complete genetic scan (deCODEme) with 1.2 million SNPs (Illumina Infinium HumanIM chip) for $1,100 USD. Demo. data download should be possible.


Comparisons & Future

23andMe v3 - Family Finder v2

23andMe v3 (960,545 SNPs) to Family Finder v2 (726,183 SNPs) in Dec. 2011.[3]:

  • 699,674 in common
  • 260,871 on 23andMe v3 but not Family Finder v2
  • 26,509 on Family Finder v2 but not 23andMe v3

Possible new offers

  • Illumina HumanOmni5-Quad BeadChip Kit: 4.3 million SNPs + 0.5 million custom SNPs (6x Illumina OmniExpress, SNPs selected from the International HapMap and 1000 Genomes Projects!), the kit should be available for companies in 2012.
  • FTDNA WTY v2: FTDNA 454 testing data (since Nov. 2011), 8 million bp (30x WTY v1), prices goal under $1000, not available (spring 2012)
  • whole genome sequencing in one day and for under $1,000: Illumina HiSeq 2500, Life Technologies Ion Proton Sequencer

References

  1. Cynthia (CeCe) Moore, Family Tree DNA's 7th International Conference on Genetic Genealogy- Day One , November 7, 2011, http://www.yourgeneticgenealogist.com/2011/11/family-tree-dnas-7th-international.html
  2. Thomas Krahn, Nov. 2011, http://www.dna-fingerprint.com/static/FTDNA-Conference-2011-WalkThroughY.pdf
  3. James Lick, Comparing v3 SNP List to v2, deCODE, Family Finder, DNA-Forums.org, 06 December 2011 (Offline)